RAPID Slit Seal, 96 well plate seal

Instant Self-Closing Seal

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The RAPID Slit Seal is a resistant, instant self-closing 96-well plate seal. The adhesive-free, pre-cut slits made of silicone and PET allows easy insertion and withdrawal of pipette tips and sampling needles without catching and dragging. The RAPID Slit Seal is proven to prevent solvent evaporation and cross-contamination. Acrylic-based adhesive is not above wells to prevent sample leaching. Seal can be easily applied and removed. Suggested applications include automated pipetting and liquid handling, SPE, HPLC, LC/MS, cell culturing and ADME.

“We run quite a lot of samples with our mass spec, which is why some people in our lab prefer to use the autosampler plate for the samples so that they can just run 96 samples in one sitting…The plate seals are working perfectly for our application.”

Testimonial from Danica-Mae Manalo, Proteomics Lab, Cedars-Sinai Medical Center



Product Summary


  • Self-closes instantly
  • No cross-contamination between wells
  • Allows next day analysis
  • No adhesive on well spots
  • Pipette tips insert easily with less friction
  • Reduce solvent evaporation


  • Automated Single Molecule Imaging
  • Cell Culturing
  • BioChemical Assays
  • Incubation
  • Vortex
  • Automated Pipetting and Liquid
  • Handling
  • SPE
  • HPLC and LC/MS
  • ADME
  • DNA Extraction


  • Size: 80 mm x 122 mm (96-well format)
  • Material: PET, Silicone
  • Adhesive: Acrylic based (no adhesive over well spots)
  • Functional temperature range: -80°C to +100°C
  • No PCR inhibition
  • If DNA-free certification is needed, please contact us





Differences from Silicone Mats:

  • Pre-cut slits open easily, and PET layer reduces friction for very easy handling.
  • Lower cost than silicone mats.


Very Effective at Preventing Evaporation:

  • After 22 hours, 95% of 150 µL water will remain at 37°C
  • After 22 hours, 95% of 150 µL of Acetonitrile will remain at 4°C

     Data Analysis Sheet

     Product Manual



LC-MS/MS-based enzyme assay for lysosomal acid lipase using dried blood spots

Mari Ohira, Marianne Barr, Torayuki Okuyama, Ryuichi Mashima

Molecular Genetics and Metabolism Reports. Volume 33, December 2022, 100913

Interested in other publications?  You can read them from here!






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