BioChromato’s Approach to Evaporation Automation in the Lab
Post date : 16/05/2026 Update date : 16/05/2026

Quick Overview
BioChromato currently supports evaporation workflows through two distinct approaches:
- The Smart Evaporator™ series, designed to support researchers by reducing the operational burden associated with evaporation in daily laboratory work
- The Smart Evaporator™ Auto Multi 140, under development as a fully automated system for high-throughput environments
Among these, the Smart Evaporator™ series represents the current, widely implemented solution for improving evaporation efficiency in laboratories.
View Smart Evaporator™ system overview↗️
Table of Contents
1. Reducing the Operational Burden of Evaporation
2. Development Toward Full Automation
3. Current Structure of BioChromato’s Approach
1. Reducing the Operational Burden of Evaporation
Smart Evaporator™ Series
The Smart Evaporator™ reduces monitoring time by preventing bumping and eliminating the need for frequent vacuum adjustments.
This enables stable and efficient evaporation across a wide range of solvents, including high-boiling solvents such as DMSO and DMF. Because the operation does not depend on continuous adjustment, evaporation results are more consistent and reproducible.
In practice, researchers can start the run and step away from the instrument.
The Smart Evaporator™ series is designed to address the operational burden associated with evaporation in daily laboratory workflows.
Its VVC (Vacuum Vortex Concentration) method creates controlled spiral airflow within the sample container, enabling stable evaporation behavior throughout the run.
This mechanism:
- Increases the liquid surface area
- Maintains stable evaporation conditions
- Suppresses sudden boiling events
As a result:
- Frequent vacuum adjustment is unnecessary
- Stable operation is maintained during evaporation
- Variability caused by operator intervention is reduced
The workflow becomes:
- Set the sample
- Start the run
- Return after completion
This allows evaporation to proceed in parallel with other laboratory tasks.
The Smart Evaporator™ series is also introduced in some applications as a “DMSO evaporator”, reflecting its ability to support stable and efficient evaporation of high-boiling solvents such as DMSO and DMF.
Positioning:
A practical tool designed to support researchers in day-to-day laboratory work by reducing the operational burden associated with evaporation while improving consistency and reproducibility.
The video below shows how evaporation can proceed without continuous monitoring once the run starts.
This is how evaporation can run in parallel with other laboratory work.
2. Development Toward Full Automation
Smart Evaporator™ Auto Multi 140
While the Smart Evaporator™ series focuses on reducing the operational burden associated with evaporation in daily workflows, BioChromato is also developing a system for full automation in high-throughput environments.
The Smart Evaporator™ Auto Multi 140 is currently in the product development stage, and availability in the U.S. market has not yet been determined.
The system was first unveiled at the JASIS 2024 exhibition in Japan, where it attracted strong interest from attendees.
The Smart Evaporator™ Auto Multi 140 is designed to support fully automated concentration workflows through features such as:
- One-button fully automated concentration
- Continuous concentration of up to 140 samples
- Bumping suppression during evaporation
- Support for DMSO, DMF, and water
- Supports up to 10 mL samples and four container types, including vials.
- Auto-sampling and auto-stop functions
- Barcode reader for sample tracking
- Weighing functionality for process monitoring
- Increased evaporation efficiency through optimized airflow control
These functions are intended to reduce manual handling and support stable operation in high-throughput laboratory environments.
The integration of weighing and monitoring functions is intended to support:
- Real-time tracking of evaporation progress
- Improved process control
- Reproducible operation across large sample sets

3. Current Structure of BioChromato’s Approach
BioChromato’s current approach can be understood in two layers:
Workflow Support (Smart Evaporator™ Series)
- Reduce monitoring time
- Reduce operational burden during evaporation
- Improve consistency and reproducibility
- Support flexible daily laboratory workflows
Full Automation (Auto Multi 140)
- Enable continuous high-throughput processing
- Integrate monitoring and tracking functions
- Reduce manual handling at larger scale
Together, these approaches are intended to reduce time spent on evaporation-related tasks and support more efficient research activities.
4. FAQ
What is the Smart Evaporator™?
The Smart Evaporator™ is an evaporation system designed to concentrate samples under reduced pressure in combination with a vacuum pump. Its proprietary “Spiral Plug” helps suppress bumping and enables stable evaporation with reduced monitoring and adjustment.
What is the Smart Evaporator™ designed for?
The Smart Evaporator™ is designed to reduce the operational burden associated with evaporation, including monitoring and adjustment during the run.
How does Smart Evaporator™ reduce monitoring time?
By preventing bumping and minimizing the need for vacuum adjustment, evaporation can proceed stably without continuous supervision.
Can Smart Evaporator™ handle DMSO and DMF?
Yes. The system supports stable and efficient evaporation of high-boiling solvents such as DMSO and DMF.
Does reducing adjustment improve reproducibility?
Yes. Reduced operator intervention helps maintain more consistent evaporation conditions between runs.
Is the Smart Evaporator™ Auto Multi 140 currently available in the U.S.?
The Smart Evaporator™ Auto Multi 140 is currently under development, and availability in the U.S. market has not yet been determined.
Explore Smart Evaporator™ in Practice
View the Smart Evaporator™ series↗️
Request a 20-minute online demo to see how stable evaporation can fit into your workflow.
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