How does the Smart Evaporator work?

Smart Evaporator uses the VVC method(*) the world’s first concentration method that enables to remove DMSO and DMF, which have been said to be difficult or time-consuming to concentrate.


Have you ever given up on using DMSO or DMF because of the difficulty of dividing or freeze-drying after use?


With Smart Evaporator, you can easily concentrate solvents that you have given up on, expanding the range of solvents you can use.  In fact, more than half of our customers use Smart Evaporator because of its ability to remove DMSO and DMF.


It has been implemented in a wide range of fields and applications, including chemical biology, complex chemistry, material science, food analysis, analytical chemistry, bio-imaging, and sample recovery when DMSO is used in NMR.
*VVC method: Vacuum Vortex Concentration method



Why can DMSO be removed?

Smart Evaporator’s VVC method, Vacuum Vortex Concentration, makes it possible to remove DMSO.
The spiral airflow created by the special concentrator plug “Spiral Plug” supports rapid solvent removal.



Principal of Vacuum Vortex Concentration

1. Vacuum suction with a pump

Vacuum suction is initiated by a vacuum pump in the same way as in conventional rotary evaporators.

2. Gas influx through a spiral slit on a Spiral Plug

The Spiral Plug has a special groove (slit) carved on it.  When the vacuum pump starts suctioning, the gas from the surrounding air passes through the slit and flows into the container.

3. Generating spiral air flow

The inflowing gas spirals inside the vessel, creating an airflow inside the vessel.

4. Increasing the contact surface area between liquid and gas

The generated spiral air flow agitates the sample in the vessel. Then the surface area of the agitated sample increases.

5. Promoting solvent volatilization

This is a special technique in which volatilization is promoted by the increase of surface area caused by the spiral airflow.



Concentration speed chart

The following is an example of the concentration speed at which 5 mL of DMSO or DMF is concentrated in a 20 mL vial. DMSO, which is difficult to concentrate easily, can be concentrated in just over 3 hours. (*Data obtained with gas replacement)

Solvent / Quantity  Suction Flow Rate  40℃ 70℃
Water/5mL (20mL vial) 29~30L/min 49 min. 28 min.
DMF/5mL (20mL vial) 20~30L/min 43 min. 24 min.
DMSO/5mL (20mL vial) 23~30L/min 195 min. 69 min.
NMP/5mL (20mL vial) 25~30L/min NA 71 min.


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