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For those who want hassle-free solvent evaporation

The Smart Evaporator™ The solvent evaporator
for quick and easy evaporation
of DMSO, DMF, and water.

BioChromato’s Smart Evaporator™ saves time and cost by removing solvents quickly and easily.
DMSO, DMF and even water are easily removed without the risk of bumping.
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  • Over 2,000 units of the installed
  • Grand Prize of the 42nd Invention Award
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*1 Total worldwide installations of all Smart Evaporator™ models in universities, public institutions, and private companies. Two hundred installations in the USA. (as of April 2023) *2 The 42nd Invention Award in 2017 (the Japan Society for the Advancement of Inventions)

Customer Challenges : Common Issues with Rotary Evaporators

Have you ever given up using DMSO, DMF, or water because of the time it takes to remove them?
01
The fear of ‘bumping’ during the evaporation often requires continuous monitoring of the rotary evaporator.
We do not want to lose valuable samples by bumping…
Issue 1
Solution 01

Smart Evaporator™ drastically reduces monitoring person-hours and time.

The Smart Evaporator™ employs a unique Spiral Plug design that keeps the vessel non-vacuumed. This design, coupled with gas flowing into the vessel, creates a spiral airflow, expanding the solvent’s surface area for facilitating solvent removal. Tough solvents like water, DMSO, and DMF can also be removed safely without bumping risk.
02
Giving up on DMSO or DMF removal
I want to use DMSO or DMF, but it takes considerable time with Rotavap…
Issue 2
Solution 02

New solvent removal technology “VVC-Vacuum Vortex Concentration” realizes stable solvent removal.

The spiral airflow created by the unique Spiral Plug supports rapid solvent removal. Even difficult solvents such as water, DMSO, and DMF can be removed quickly.
03
Time-consuming to transfer between containers during the process
It's hard to transfer to another container, and sample loss is also a concern…
Issue 3
Solution 03

No need to transfer samples. Sample loss and cleaning time are reduced.

With the Smart Evaporator™, there’s no need to transfer solvents to storage containers or microtubes. It’s designed for flexibility, allowing the use of various containers for efficient solvent removal.

Interested in learning more?
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The Smart Evaporator™ Principle

The Smart Evaporator™ features the world’s first vacuum vortexing technology that agitates the sample solvent, increasing its surface area and accelerating the evaporation speed.

Vacuum Vortex Concentration

Vacuum Vortex Concentration

Principle of Vacuum Vortex Concentration

  • 1

    Vacuum suction with a pump

    Vacuum suction is initiated by a vacuum pump in the same way as in conventional rotary evaporators.
  • 2

    Gas influx through a spiral slit on a Spiral Plug

    The Spiral Plug has a special groove (slit) carved on it. When the vacuum pump starts suctioning, the gas from the surrounding air passes through the slit and flows into the container.
  • 3

    Generating spiral air flow

    The inflowing gas spirals inside the vessel, creating an airflow inside the vessel.
  • 4

    Increasing the contact surface area between liquid and gas

    Generated spiral air flow agitates the sample in the vessel. Then the surface area of the agitated sample increases.
  • 5

    Promoting solvent volatilization

    This is a special technique in which volatilization is promoted by the increase of surface area caused by the spiral airflow.

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Evaporation Speed Chart

The Smart Evaporator™ evaporates a wide variety of solvents from low to high boiling points. Even high boiling point solvents that are difficult to remove with conventional rotary evaporators can be removed.
  • Solvent / 5mL
  • Suction Flow Rate
  • 40°C
  • 70°C
  • Hexane

    15L/min
    3min
    3min
  • Acetone

    15L/min
    4min
    3min
  • Ethyl acetate

    15L/min
    6min
    5min
  • Acetonitrile

    15L/min
    9min
    8min
  • Methanol

    15L/min
    10min
    6min
  • Ethanol

    15L/min
    10min
    6min
  • Water

    29~30L/min
    49min
    28min
  • DMF

    20~30L/min
    43min
    24min
  • DMSO

    23~30L/min
    195min
    69min
  • NMP

    25~30L/min
    N/A
    71min

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The Smart Evaporator™ Specifications

Here are the specifications for the Smart Evaporator™. Please note that the specifications provided here are for the single-sample model. We also offer multi-sample models with varying capabilities. For more detailed information, please download our official catalog and review its contents.
  • Product Name

    Smart Evaporator C1
  • Heater shape & size

    Circle shaped, φ69mm
  • Heater temperature range

    Room temperature ~ 100°C
  • Gas Purge

  • Inner mouth diameter of
    compatible containers

    φ4~32mm
  • Color

    1 color (Sky)
  • Size (mm)

    W220 x D227 x H382 (except protruded parts)
  • Weight

    4.3kg
  • Operating environment

    Temperature: 10℃~ 40°C Humidity: 20~80%

Interested in learning more?
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Case Studies

A wide range of customers from universities to private companies uses our products.
Smart Evaporator C1 works remarkably. It has a potential to cope with significant unmet needs.
Case Study 01

Smart Evaporator C1 works remarkably. It has a potential to cope with significant unmet needs.

We needed to produce a chemical compound in DMSO-containing water, from which the compound has to be isolated as a dry powder. Technically DMSO removal is said as possible by lyophilization, however DMSO removal takes forever and incomplete. DMSO removal for practical time/scale is truly a significant unmet need from pharmaceutical aspect.
The Smart Evaporator™ has cut down the time I produce product by 75%.
Case Study 02

The Smart Evaporator™ has cut down the time I produce product by 75%.

Before the Smart Evaporator™, from reaction to purified product could take 2 weeks. Then my 2-week timeline has been cut down to 4-5 days. This means I am producing faster, and thus, progressing science. I am eternally grateful for this device and all of the time it has saved me.
Time reduced for concentration, drying and storage! Indispensable part of our laboratory to handle a large number of samples.
Case Study 03

Time reduced for concentration, drying and storage! Indispensable part of our laboratory to handle a large number of samples.

If the solvent is completely evaporated on concentration by a rotary evaporator, it will be difficult to process the sample when we try to transfer sample to a screw tube for concentration, drying, and storage, and the amount of sample recovery is further reduced. The Smart Evaporator™ is utilized to complete the concentration process due to its ease of sample concentration and drying operation.

Interested in learning more?
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4 Steps to Introduction

We will propose the most suitable model for your specific application.
Download the product information
Step 01

Download the product information

No matter whether you have a product you are interested in or would like to discuss your current issues for the time being, please feel free to download the information from the website. We will contact you shortly.
Meeting・Demonstration
Step 02

Meeting・Demonstration

Please tell us about your current issues. We will make the best proposal for you. We can also send you a demo unit as needed, allowing you to actually try it out for yourself.
Quotation
Step 03

Quotation

We will provide a quotation for the most suitable model. If necessary, we will also guide you through our vacuum pump offerings.
Ordering
Step 04

Ordering

Delivery time varies depending on the model, but is approximately a minimum of 2 weeks to 2 months.
*Depends on the region and situation.

FAQ

Here you will find answers to frequently asked questions from our customers.

Q1 How does the Smart Evaporator™ ensure a bump-free evaporation?

A
The Smart Evaporator™ is engineered to drastically minimize the risk of bumping. A unique groove embedded in the Spiral Plug’s surface, in conjunction with a low vacuum maintained internally, prevents the pressure from dropping to a level that would cause the solvent to boil. Additionally, this groove facilitates the inflow of air, generating a spiral airflow which intensively stirs the sample. As a result, the bumping risk is significantly reduced.

Q2 What are the necessary preparations required to start the evaporation process?

A
There are several essential components needed to start the evaporation process. These include the sample container for evaporation, the vacuum pump, and the vacuum hoses. Once these elements are properly set up with the Smart Evaporator™, the system is ready for operation.

Q3 What types of containers are compatible with the Smart Evaporator™?

A
The Smart Evaporator™ can hold containers with an internal mouth diameter between 4-32mm and a maximum height of 120mm. To make things easier, it’s suggested to use microtubes or vials, as this means you won’t have to move samples from one container to another. Please note, the preparation of these containers is not included and should be prepared on your own.

Q4 Is it possible to perform evaporation under a nitrogen atmosphere with the Smart Evaporator™?

A
Yes, the Smart Evaporator™ can be gas-filled with nitrogen. However, a separate gas supply source must be prepared by the customer.

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